MyBioSource.com's P2RX1 Antibody (C-term) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The P2RX1 Antibody (C-term) was generated using P2RX1, P2X1, and Pdcd3 as the antigen and it reacts with Human, and Rat.
Description
The product of this gene belongs to the family of
purinoceptors for ATP. This receptor functions as a ligand-gated
ion channel with relatively high calcium permeability. Binding to
ATP mediates synaptic transmission between neurons and from neurons
to smooth muscle, being responsible, for example, for sympathetic
vasoconstriction in small arteries, arterioles and vas deferens.
Mouse studies suggest that this receptor is essential for normal
male reproductive function. It is possible that the development of
selective antagonists for this receptor may provide an effective
non-hormonal male contraceptive pill